This is a small guide for resolve permanently the conflict between Skype and S4 league. You should know that from version 5.0 onwards has been deprived of the opportunity to block the automatic update, but this is not provided for earlier versions, then...
Step 1: download version 188.8.131.52 from this site -> http://filehippo.com/download_skype/8287/
Step 2: unistall your skype version currently installed.
Step 3: Install version 184.108.40.206.
Step 4: Log in with your id and password. Then click on tools ---> options and set Skype as in the picture.